In other parts of the body, immune cells send antibodies into the bloodstream against pathogens that appear there. Because of their encapsulation, this is not possible in the brain itself, and defense must be provided by the meninges.
Researchers at Cambridge University wanted to see how this worked and were surprised to see that the meninges learned this trade in the gut. In the meninges, they found antibodies that are only found elsewhere in the intestinal mucosa. It turns out that the immune cells that make these antibodies have direct relatives in the gut. Researchers have discovered that they are actually coming from. In mice whose defenses were turned off in the gut, this was also not found in the meninges. Once they triggered the defense in the mouse gut, it also began to act in the mouse meninges.
The Defenders
Courage sends out the defenders, literally. Not surprisingly, researchers say in the journal natureBecause if the intestines are damaged and pathogens leak out, they can have dire consequences for the brain. It is good that meninges can have defenders who are aware of the danger. If you eliminate those defenders, you’ll instantly see that things go wrong in the brain.
What’s in his head, not his butt, is the Dutch proverb. Now it appears the opposite is true.
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What the gut tells us
The rich bacteria life in the gut has been linked to everything from obesity to depression and Alzheimer’s disease. If you look closely at all of the claims, how much science is left?
